showmacster
nice enhancements - drop in movies, screen capture, annotations ...
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I was involved in the wetpaint beta a few months ago. One of the better hosted wikis with wywisyg editing. It doesn't work with Safari - just Firefox and IE - but is difficult to beat for someone looking for an easy-to-use low end solution.
vyew
I was on a conference with Campfire -- simple and it seemed to work well with about 20 other people.
now free
and, oddly enough, they have kept the OS X client.
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ePost
p2p/secure/spamless
more on the subject
3 Canadian universities have funding to investigate the use of social software for teaching.
this is a clear cut case
Creative Commons is setting up a wiki on free culture.